They are the mainstay of the current management of chronic obstructive pulmonary disease (COPD) and are critical in the symptomatic management of asthma, although controversies around the use of these drugs remain. 18 They make breathing easier for people with asthma or other lung conditions.. Bronchodilators include short acting beta2-agonists such as albuterol, long-acting beta2-agonists (such as salmeterol, formoterol), anticholinergic agents (eg, ipratropium) and theophylline. There is therefore considerable interest in understanding how to optimize the use of our existing classes of bronchodilator and in identifying novel classes of bronchodilator drugs. Bronchodilators … … Original PPT modified by: Anita A. Kovalsky, R.N., M.N.Ed.. In asthma and COPD, bronchoconstriction and mucus secretion are increased and the airways become hyperresponsive to contractile agents. They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. Bronchodilators are the mainstay therapy in COPD, as they increase expiratory flow by decreasing airway smooth muscle tone, thus leading to enhanced lung emptying. Expectorants are drugs that liquefy the lower respiratory tract secretions. They are used for the symptomatic relief of respiratory conditions characterized by a dry, nonproductive cough.. Mucolytics work to break down mucus to aid high-risk respiratory patients in coughing up thick, tenacious secretions.. Professor of Nursing. Bronchodilators (Contd) Xanthine Derivatives Main xanthine used clinically is theophylline Theophylline is a bronchodilator which relaxes smooth muscle of the bronchi, it is used for reversible airway obstruction One proposed mechanism of action is that it acts by inhibiting phosphodiesterase, thereby increasing cAMP, leading to bronchodialtion. Bronchodilators are drugs that open up (dilate) the breathing passages by relaxing the bronchial smooth muscle. Bronchodilators are central in the treatment of of airways disorders. Start studying PHARMACOLOGY: ANTICHOLINERGIC BRONCHODILATORS. The cholinergic blocking drug ipratropium bromide (Atrovent) is used for bronchospasm associated with COPD, chronic bronchitis, and emphysema in emergent situations. Bronchodilators Lilley Pharmacology Text: Chapter 35. Bronchodilators remain the cornerstone of the treatment of airway disorders such as asthma and chronic obstructive pulmonary disease (COPD). View Test Prep - Cardio4e_PPT_005_Final.pptx from RESC 3731 at Youngstown State University. Therefore, it is of utmost importance to describe the pharmacological basis of therapeutics in order to maximize the benefits and Sympathomimetic Bronchodilators: Actions and Uses. 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